March 2024

March 2024


Carbapenem-resistant Klebsiella pneumoniae: the role of plasmids in emergence, dissemination, and evolution of a major clinical challenge

Klebsiella pneumoniae is considered as an important nosocomial pathogen contributing to healthcare-associated infections and some community acquired infections. In addition, K. pneumoniae tends to acquire resistance to several classes of antibiotics including carbapenems by the transfer of different genes encoding β-lactamases (carbapenemases) capable of breaking them down. This process is promoted by various  carbapenemase-encoding plasmids that participate in the spread of resistance.

Suggested by our guest Dr. Alberto Antonelli for you.

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