April 2024

April 2024

Complex Magnetic Fields represent an eco-sustainable technology to counteract the resistant Candida albicans growth without affecting the human gingival fibroblasts

Complex Magnetic Fields (CMFs) affect the resistant Candida albicans viability, representing a new strategy for Candida infections. The prolonged use of antifungal therapy for the oral candidiasis has led to C. albicans adaptation to the drugs developing resistance/tolerance and representing a global challenge for oral treatment. CMFs are able to reduce the C. albicans biofilm formation with a remarkable killing action also inducing an alteration of lipidic structure of the membrane and improve the wound healing. These significant effects are obtained without interfering with the hGFs proliferation and viability. These interesting results suggest the use of the CMFs for the treatment of C. albicans biofilm infections underlying their eco-sustainability because their application does not need the use of adjunctive substances or drugs, avoiding the disposal problem with no environmental impact being fully in line with the 2030 agenda for the sustainable development. 

Suggested by Silvia Di Lodovico

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